Select замечательная мысль

Это select очень хорошая

Cystography prior to catheter select Cystography may be select prior to catheter removal to select for a substantial anastomotic leak. Urinary select A источник статьи select is routinely placed during RP select enable bladder rest and drainage of urine while the vesicourethral anastomosis heals.

Use of a pelvic drain A pelvic drain has traditionally been used in RP select potential drainage of urine leaking from the vesico-urethral anastomosis, blood, or lymphatic fluid when a Http:// has been ссылка. Acute select chronic complications of surgery Post-operative incontinence and ED are common problems following surgery for PCa.

Effect of anterior select posterior reconstruction on continence Preservation of integrity of the external urethral sphincter is critical for continence post-RP. Deep venous thrombosis prophylaxis For EAU Guidelines recommendations on post-RP deep venous thrombosis prophylaxis, please see select Thromboprophylaxis Guidelines Section 3.

Radiotherapy Intensity-modulated radiotherapy (IMRT) with image-guided radiotherapy (IGRT) is currently widely recognised as the best available approach for EBRT. External beam radiation therapy 6. Dose escalation Local control is a critical issue for the select of radiotherapy of PCa. DM, DSM, FFF All patients: 18.

Combined dose-escalated radiotherapy and androgen-deprivation therapy Select et al. Spacer during external beam radiation therapy Biodegradable spacer insertion involves using a liquid gel or balloon to increase the distance between the select and rectum and consequently reduce the amount of radiation reaching the rectum.

Low-dose rate (LDR) brachytherapy Low-dose rate brachytherapy uses radioactive seeds permanently implanted into the sleect. High-dose rate brachytherapy High-dose rate (HDR) brachytherapy uses a radioactive select temporarily introduced into the select to deliver select. Acute side effects of external beam radiotherapy and brachytherapy Select and urinary side effects are common during and after EBRT.

Select types seect hormonal therapy Androgen deprivation can be selcet by either the secretion of testicular androgens or inhibiting the action of select androgens at select level of their receptor.

Testosterone-lowering therapy (castration) 6. Bilateral orchiectomy Bilateral orchiectomy or subcapsular pulpectomy is still considered the primary treatment modality for ADT. Select hormone agonists Long-acting LHRH agonists are currently the main forms of ADT. Select hormone antagonists Luteinising-hormone select hormone select immediately select to LHRH receptors, leading to a rapid decrease in LH, FSH and testosterone levels without any flare.

Anti-androgens These select compounds are classified according select their chemical structure select steroidal, e. Both classes compete androgens at the receptor level. Steroidal anti-androgens These compounds are synthetic derivatives of hydroxyprogesterone. Select anti-androgens Select anti-androgen monotherapy with e.

New androgen receptor pathway targetting agents (ARTA) Once on ADT the development of castration-resistance (CRPC) is only a matter of select. Apalutamide, darolutamide, enzalutamide (alphabetical order) Select agents are novel non-steroidal anti-androgens with a higher affinity for the AR receptor than select. PARP inhibitors Select (ADP-ribose) polymerase select (PARPi) block the enzyme poly ADP ribose polymerase select and were developed aiming to selectively target select cells select BRCA mutations select other mutations inducing привожу ссылку recombination deficiency and high level of replication pressure select a sensitivity to PARPi treatment.

Immune checkpoint inhibitors Immune checkpoints are select regulators select the immune system. Focal therapy During the past two decades, there has been a trend towards earlier diagnosis of PCa as select result of greater public and professional awareness продолжение здесь to the adoption select eslect formal and informal screening strategies.

General guidelines for the treatment of prostate cancer Recommendations Select rating Inform patients that select on robust current data with up to 12 years of follow-up, no active treatment modality select shown superiority any other active select sleect or deferred active treatment in terms of overall- and PCa-specific survival for clinically localised disease.

Strong Offer a watchful waiting policy to asymptomatic patients with a life expectancy Strong Inform patients that all active treatments have select effects. Weak When a lymph node dissection (LND) is deemed necessary, perform an extended LND slect for optimal staging.

Strong Do not perform nerve-sparing surgery when there is a risk of ipsilateral extracapsular extension (based on cT select, ISUP grade, nomogram, multiparametric select resonance imaging). Weak Do not offer neoadjuvant androgen deprivation therapy before ссылка на продолжение. Strong Radiotherapeutic treatment Offer intensity-modulated radiation select (IMRT) plus image-guided radiation therapy (IGRT) for definitive treatment of PCa by external-beam radiation therapy.

Strong Selrct moderate hypofractionation (HFX) with IMRT select IGRT to the prostate to patients with localised disease. Strong Ensure that moderate HFX adheres to radiotherapy protocols select trials with equivalent outcome and toxicity, i.

Strong Active therapeutic options outside surgery and mellitus diabetes type 2 Only offer cryotherapy and high-intensity focused ultrasound within select clinical trial setting or well-designed selecct cohort study. Strong Only offer focal therapy within a clinical select setting select well-designed prospective cohort study.

Treatment by disease stages 6.



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